Molecular pathways for water fluxes in mouse choroid plexus epithelial cells (1182.3)
نویسندگان
چکیده
منابع مشابه
Epithelial pathways in choroid plexus electrolyte transport.
A stable intraventricular milieu is crucial for maintaining normal neuronal function. The choroid plexus epithelium produces the cerebrospinal fluid and in doing so influences the chemical composition of the interstitial fluid of the brain. Here, we review the molecular pathways involved in transport of the electrolytes Na+, K+, Cl-, and HCO3(-)across the choroid plexus epithelium.
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The choroid plexus (ChP) epithelium is a multifunctional tissue found in the ventricles of the brain. The major function of the ChP epithelium is to produce cerebrospinal fluid (CSF) that bathes and nourishes the central nervous system (CNS). In addition to the CSF, ChP epithelial cells (CPECs) produce and secrete numerous neurotrophic factors that support brain homeostasis, such as adult hippo...
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Abstract Background: Choroid plexus (CP) is a branched structure made up of a single layer of epithelial cells and blood capillaries, forming the blood-CSF-barrier. The CSF (cerebrospinal fluid) is mainly produced from the CP. Aquaporin1 (AQP1), water channels that are highly expressed on the apical side of the membrane in choroid plexus, have a major role in mediating water transport across th...
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CPCs are a relatively common finding during the second trimester sonography. when a choroid plexus cyst is identified, the presence of structural malformation and other sonographic markers of aneuploidy should be assessed with a detailed fetal anatomic survey performed by an experienced person. if no other sonographic abnormalities are present, the CPC is considered isolated. given the consider...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2014
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.28.1_supplement.1182.3